Primary Identifier | MGI:1352499 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 29812 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Involved in decidualization. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; forelimb interdigital region mesenchyme; genitourinary system; and thymus primordium. Orthologous to human NDRG3 (NDRG family member 3). PHENOTYPE: Homozygous mutation of this gene results in lethality before weaning. Mice heterozygous for another null allele exhibit reduced male fertility due to impaired double strand break repair in spermatocytes. [provided by MGI curators] |