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Protein Coding Gene : Hrh3 histamine receptor H3

Primary Identifier  MGI:2139279 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  99296
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including G protein-coupled amine receptor activity; amine binding activity; and heterocyclic compound binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; learning or memory; and regulation of secretion. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in dendrite; plasma membrane; and synapse. Is expressed in brain. Orthologous to human HRH3 (histamine receptor H3).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit reduced locomotor activity and body temperature, and attenuated behavioral responses to the drugs thioperamide, methamphetamine, and scopolamine. [provided by MGI curators]
  • synonyms:
  • AW049250,
  • MGI:1309474,
  • histamine receptor H3,
  • experimental allergic encephalomyelitis susceptibility 8,
  • Hrh3,
  • Eae8,
  • expressed sequence AW049250

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For