| Primary Identifier | MGI:1919857 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 72607 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including BAT3 complex binding activity; peptidase activity; and proteasome binding activity. Predicted to be involved in several processes, including maintenance of unfolded protein; positive regulation of ERAD pathway; and protein stabilization. Predicted to act upstream of or within autophagy and proteolysis. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Orthologous to human USP13 (ubiquitin specific peptidase 13). PHENOTYPE: Mice homozygous for a null allele exhibit increased susceptibility to LPS- or Pseudomonas aeruginosa (strain PA103)- induced lung inflammation and injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
