| Primary Identifier | MGI:2153183 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 140493 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable calmodulin binding activity; inward rectifier potassium channel activity; and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport. Located in cytoplasm and plasma membrane. Is expressed in brain; early conceptus; and heart. Human ortholog(s) of this gene implicated in paranoid schizophrenia and schizophrenia. Orthologous to human KCNN3 (potassium calcium-activated channel subfamily N member 3). PHENOTYPE: Mice homozygous for an insertion of a tetracycline-regulated gene switch display no overt phenotype when expression is abolished by doxycycline treatment; in contrast, untreated homozygotes show abnormal respiratory responses to hypoxia, impaired parturition, and pregnancy-related premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
