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Protein Coding Gene : S100a10 S100 calcium binding protein A10 (calpactin)

Primary Identifier  MGI:1339468 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  20194
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including calcium-dependent protein binding activity; protein homodimerization activity; and transmembrane transporter binding activity. Involved in mRNA transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and regulation of neurogenesis. Located in cell surface and plasma membrane. Part of RNA polymerase II transcription regulator complex and plasma membrane protein complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart and pericardium; and sensory organ. Orthologous to human S100A10 (S100 calcium binding protein A10).
PHENOTYPE: Mice homozygous for a knock-out allele display a depression-like phenotype, decreased responsiveness to 5-HT1B receptor agonists, and reduced behavioral reactions to an antidepressant. [provided by MGI curators]
  • synonyms:
  • Cal1l,
  • MGI:88247,
  • CAL12,
  • calpactin I light chain,
  • S100 calcium binding protein A10 (calpactin),
  • MGD-MRK-1728,
  • AA409961,
  • MGI:2139857,
  • expressed sequence AL024248,
  • S100a10,
  • p10,
  • CLP11,
  • MGI:2139574,
  • expressed sequence AA409961,
  • AL024248,
  • 42C

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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2 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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