| Primary Identifier | MGI:1341265 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 108058 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables calmodulin-dependent protein kinase activity and transmembrane transporter binding activity. Involved in regulation of relaxation of cardiac muscle. Acts upstream of or within several processes, including G1/S transition of mitotic cell cycle; cardiac muscle contraction; and regulation of sodium ion transport. Located in several cellular components, including T-tubule; axon initial segment; and intercalated disc. Is expressed in several structures, including central nervous system; heart ventricle; olfactory epithelium; renal vasculature; and retina. Orthologous to human CAMK2D (calcium/calmodulin dependent protein kinase II delta). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced response to heart induced stress. Mice homozygous for an allele that produces an oxidant-resistant product exhibit reduced response to myocardial infarction in a diabetic model. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
