Primary Identifier | MGI:2140270 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 381524 |
Mgi Type | lncRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables chromatin DNA binding activity. Involved in several processes, including cellular response to oxidised low-density lipoprotein particle stimulus; cholesterol efflux; and cholesterol homeostasis. Located in nucleus. Part of chromatin. PHENOTYPE: Homozygous knockout affects macrophage cholesterol metabolism and increases atherosclerosis susceptibility in mice fed Western diet. [provided by MGI curators] |