| Primary Identifier | MGI:1099786 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 13204 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable RNA helicase activity and double-stranded RNA binding activity. Involved in antiviral innate immune response and defense response to bacterium. Predicted to be located in nuclear speck. Predicted to be part of U12-type spliceosomal complex and U2-type post-mRNA release spliceosomal complex. Is expressed in several structures, including aorta; forelimb bud; future brain; liver; and spleen. Orthologous to human DHX15 (DEAH-box helicase 15). PHENOTYPE: Mice homozygous for a conditional allele activated in lymphocytes exhibit impaired development, reduced B cell numbers, reduced B cell proliferation upon activation and impaired IgG1 response to NP-CGG. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
