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Protein Coding Gene : Nsun7 NOL1/NOP2/Sun domain family, member 7

Primary Identifier  MGI:1918168 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  70918
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable RNA binding activity and S-adenosylmethionine-dependent methyltransferase activity. Acts upstream of or within flagellated sperm motility and sperm mitochondrion organization. Is expressed in several structures, including branchial arch; central nervous system; extraembryonic component; neural ectoderm; and sensory organ. Orthologous to human NSUN7 (NOP2/Sun RNA methyltransferase family member 7).
PHENOTYPE: Males homozygous for an ENU-induced mutation are either infertile or subfertile. Mutant sperm exhibit poor progressive motility linked to rigidity of the flagellar midpiece and abnormal electron density patterns in the mitochondrial sheath. [provided by MGI curators]
  • synonyms:
  • NOL1/NOP2/Sun domain family, member 7,
  • 4921525L17Rik,
  • Nsun7,
  • RIKEN cDNA 4921525L17 gene

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Genome

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4 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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