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Protein Coding Gene : G3bp2 G3BP stress granule assembly factor 2

Primary Identifier  MGI:2442040 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  23881
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable mRNA binding activity and molecular condensate scaffold activity. Predicted to be involved in positive regulation of stress granule assembly; protein homooligomerization; and stress granule assembly. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be located in cytoplasmic stress granule. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytosol. Is expressed in several structures, including central nervous system; ovary; sensory organ; and tooth. Orthologous to human G3BP2 (G3BP stress granule assembly factor 2).
PHENOTYPE: Despite increased male germ cell apoptosis, male mice homozygous for a conditional allele activated in Sertoli cells or germ cells exhibit normal spermatogenesis and fertility. [provided by MGI curators]
  • synonyms:
  • expressed sequence AA409541,
  • G3BP stress granule assembly factor 2,
  • G3BP,
  • MGI:2146760,
  • G3bp2,
  • E430034L04Rik,
  • RIKEN cDNA E430034L04 gene,
  • G3BP2,
  • AA409541,
  • MGI:1346339

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For