| Primary Identifier | MGI:2140804 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 243168 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and steroid dehydrogenase activity. Predicted to act upstream of or within positive regulation of lipid biosynthetic process. Located in lipid droplet. Orthologous to human HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13). PHENOTYPE: Male mice homozygous for a null allele exhibit hepatic steatosis, increased liver triglyceride levels, increased lipogenesis, decreased fatty acid beta-oxidaton, and liver inflammation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
