Primary Identifier | MGI:1924223 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 231670 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable DNA binding activity. Is expressed in nervous system and neural retina. Orthologous to human FBXO21 (F-box protein 21). PHENOTYPE: Mice homozygous for a conditional allele activated in hematopoietic cells exhibit increased susceptibility to 5-FU-induced bone marrow failure and lethality. [provided by MGI curators] |