Primary Identifier | MGI:1915434 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 68184 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable mRNA binding activity. Predicted to be involved in IRES-dependent viral translational initiation; cytoplasmic translational initiation; and ribosome disassembly. Predicted to act upstream of or within translational initiation. Is expressed in embryo. Orthologous to human DENR (density regulated re-initiation and release factor). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormalities in trophoblast layer formation and trophoblast giant cell size and morphology and complete embryonic lethality during organogenesis. [provided by MGI curators] |