Primary Identifier | MGI:2686991 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 215210 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables monoatomic ion channel activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception of pain; fat cell differentiation; and protein complex oligomerization. Located in plasma membrane. Is expressed in central nervous system and ganglia. Orthologous to human TMEM120A (transmembrane protein 120A). PHENOTYPE: Mice homozygous for a conditional allele activated in DRG neurons with the non-peptidergic population exhibit reduced nocifensive behavior in response to mechanical stimuli. [provided by MGI curators] |