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Protein Coding Gene : Lmtk2 lemur tyrosine kinase 2

Primary Identifier  MGI:3036247 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  231876
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable myosin VI binding activity; protein phosphatase inhibitor activity; and protein serine/threonine kinase activity. Predicted to be involved in endosomal transport; receptor recycling; and transferrin transport. Predicted to act upstream of or within axon guidance and neurotrophin TRK receptor signaling pathway. Predicted to be located in several cellular components, including endosome; growth cone; and neuronal cell body. Is expressed in brain; olfactory cortex marginal layer; and pancreas. Orthologous to human LMTK2 (lemur tyrosine kinase 2).
PHENOTYPE: Mice homozygous for a null mutation in this gene display partial prenatal lethality, male infertility, and azoospermia. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA A330101P12 gene,
  • A330101P12Rik,
  • Lmtk2,
  • MGI:1920140,
  • AATYK2,
  • lemur tyrosine kinase 2,
  • KPI-2,
  • RIKEN cDNA 2900041G10 gene,
  • BREK,
  • 2900041G10Rik,
  • cprk,
  • KPI2

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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