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Protein Coding Gene : Ccdc136 coiled-coil domain containing 136

Primary Identifier  MGI:1918128 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  232664
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in acrosome assembly and single fertilization. Located in acrosomal membrane. Is expressed in retina outer nuclear layer. Orthologous to human CCDC136 (coiled-coil domain containing 136).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility, globozoospermia, asthenozoospermia, and decreased in vitro fertilization frequency. [provided by MGI curators]
  • synonyms:
  • 4921511K06Rik,
  • Ccdc136,
  • coiled-coil domain containing 136,
  • BC006583,
  • MGI:2385256,
  • cDNA sequence BC006583,
  • MGC:8047,
  • RIKEN cDNA 4921511K06 gene

Features --> Cross References

Genome

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0 Involved In Mutations

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0 Transgenic Expressors

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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