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Protein Coding Gene : Exoc4 exocyst complex component 4
Primary Identifier  MGI:1096376 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  20336
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables PDZ domain binding activity. Acts upstream of or within paraxial mesoderm formation and protein transmembrane transport. Located in growth cone membrane; microvillus; and myelin sheath abaxonal region. Is expressed in several structures, including central nervous system; extraembryonic component; ganglia; and retina. Orthologous to human EXOC4 (exocyst complex component 4).
PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic abnormatlities. Gastrulation is not completed and mesoderm formation is abnormal. Death occurs before E10.5. [provided by MGI curators]
  • synonyms:
  • exocyst complex component 4,
  • SEC8-like 1 (S. cerevisiae),
  • SEC8 (S. cerevisiae),
  • EST C78892,
  • Sec8l1,
  • C78892,
  • Sec8,
  • Exoc4,
  • MGI:1353571
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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