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Protein Coding Gene : Clec5a C-type lectin domain family 5, member a
Primary Identifier  MGI:1345151 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  23845
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables virus receptor activity. Involved in several processes, including innate immune response; osteoblast development; and positive regulation of cytokine production. Acts upstream of or within myeloid cell differentiation and negative regulation of myeloid cell apoptotic process. Located in cell surface. Orthologous to human CLEC5A (C-type lectin domain containing 5A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased susceptibility to induced arthritis. [provided by MGI curators]
  • synonyms:
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5,
  • Clecsf5,
  • Clec5a,
  • C-type lectin domain family 5, member a,
  • myeloid DAP12-associating lectin-1,
  • MDL-1,
  • Ly100
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