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Protein Coding Gene : Skap2 src family associated phosphoprotein 2

Primary Identifier  MGI:1889206 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  54353
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Acts upstream of or within negative regulation of cell population proliferation. Located in cytoplasm. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human SKAP2 (src kinase associated phosphoprotein 2).
PHENOTYPE: Mice homozygous for a null allele are embryonic lethal. Homozygotes for a gene-trapped allele show impaired B-cell responses and B-cell adhesion, decreased susceptibility to EAE, abnormal dendritic cell physiology, fast extinction of fear memory, and impaired social memory. [provided by MGI curators]
  • synonyms:
  • MGI:1889379,
  • BB137539,
  • EST AA960083,
  • RIKEN cDNA 2610021A10 gene,
  • Skap2,
  • Saps,
  • MGI:3035219,
  • expressed sequence BB137539,
  • RA70,
  • AA960083,
  • src family associated phosphoprotein 2,
  • mSKAP55R,
  • 2610021A10Rik,
  • SKAP-HOM,
  • MGI:1922074

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For