Primary Identifier | MGI:99252 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 13656 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; and tooth. Orthologous to human EGR4 (early growth response 4). PHENOTYPE: Male homozygous null mice are viable but infertile due to an impairment of meiosis during spermatogenesis. Females are fertile and the gross anatomy of both sexes appears normal. [provided by MGI curators] |