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Protein Coding Gene : Arl8b ADP-ribosylation factor-like 8B

Primary Identifier  MGI:1914416 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  67166
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G protein activity; guanyl ribonucleotide binding activity; and tubulin binding activity. Involved in several processes, including antigen processing and presentation of polysaccharide antigen via MHC class II; late endosome to lysosome transport; and viral exocytosis. Acts upstream of or within endosomal transport. Located in axon; lysosome; and synapse. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; limb; and sensory organ. Orthologous to human ARL8B (ADP ribosylation factor like GTPase 8B).
PHENOTYPE: Mice homozygous for a null mutation display perinatal lethality with impaired visceral yolk sac function and reduced embryo size. [provided by MGI curators]
  • synonyms:
  • 2610313E07Rik,
  • Arl10c,
  • Arl8b,
  • ADP-ribosylation factor-like 8B,
  • RIKEN cDNA 3100002J04 gene,
  • MGI:1916525,
  • RIKEN cDNA 2610313E07 gene,
  • ADP-ribosylation factor-like 10C,
  • 3100002J04Rik

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