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Protein Coding Gene : Acrbp proacrosin binding protein

Primary Identifier  MGI:1859515 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  54137
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable peptidase activator activity. Involved in acrosome assembly and fertilization. Located in acrosomal vesicle. Is expressed in testis. Orthologous to human ACRBP (acrosin binding protein).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced male fertility associated with aberrant formation of the acrosomal granule, a fragmented acrosome structure, an abnormally condensed nuclear structure, and decreased sperm motility. [provided by MGI curators]
  • synonyms:
  • OY-TES-1,
  • Acrbp,
  • proacrosin binding protein,
  • sp32

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For