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Protein Coding Gene : Ncapd2 non-SMC condensin I complex, subunit D2

Primary Identifier  MGI:1915548 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  68298
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable histone binding activity. Involved in positive regulation of chromosome segregation and positive regulation of chromosome separation. Located in condensed nuclear chromosome and pronucleus. Part of condensin complex. Is expressed in several structures, including central nervous system; retina outer nuclear layer; and salivary gland. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD2 (non-SMC condensin I complex subunit D2).
PHENOTYPE: Mice heterozygous for a null allele exhibit decreased susceptibility to AOM/DSS-induced colorectal cancer and colitis. [provided by MGI curators]
  • synonyms:
  • mKIAA0159,
  • MGI:1920064,
  • RIKEN cDNA 2810406C15 gene,
  • 2810465G24Rik,
  • RIKEN cDNA 2810465G24 gene,
  • Ncapd2,
  • non-SMC condensin I complex, subunit D2,
  • 2810406C15Rik,
  • CNAP1,
  • CAP-D2

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

5 Pathways

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Expression

Gene --> Expression annotations

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Disease

Mouse features --> Human diseases

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