| Primary Identifier | MGI:1913358 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 66108 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable NADH dehydrogenase activity. Predicted to be involved in circadian rhythm; mitochondrial respiratory chain complex I assembly; and ubiquinone-6 biosynthetic process. Located in mitochondrial inner membrane. Part of mitochondrial respiratory chain complex I. Is active in mitochondrion. Is expressed in several structures, including alimentary system; egg cylinder; genitourinary system; integumental system; and nervous system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 26. Orthologous to human NDUFA9 (NADH:ubiquinone oxidoreductase subunit A9). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
