Primary Identifier | MGI:2682314 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 330474 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables chromatin binding activity. Involved in RNA catabolic process and negative regulation of DNA-templated transcription. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; oocyte; retina; and telencephalon. Orthologous to human ZC3H4 (zinc finger CCCH-type containing 4). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality between implantation and somite formation and failure of blastocysts to hatch from the zona pellucida and form typical outgrowth colonies. [provided by MGI curators] |