| Primary Identifier | MGI:2441992 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 319197 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables G protein-coupled receptor activity. Involved in positive regulation of inflammatory response and regulation of vascular permeability. Acts upstream of or within several processes, including blood vessel development; negative regulation of angiogenesis; and response to acidic pH. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in cerebral cortex. Orthologous to human GPR4 (G protein-coupled receptor 4). PHENOTYPE: Mice homozygous for a null allele display partial neonatal and postnatal lethality, hemorrhages, impaired association of vascular smooth muscle cells with capillaries and small arteries and veins, and impaired contact between mesangial cells and renal glomerular capillaries. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
