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Protein Coding Gene : Hcst hematopoietic cell signal transducer

Primary Identifier  MGI:1344360 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  23900
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable phosphatidylinositol 3-kinase binding activity and signaling receptor binding activity. Predicted to be involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in cell surface and membrane. Is expressed in ductus deferens; epididymis; esophagus; prostate gland; and testis. Orthologous to human HCST (hematopoietic cell signal transducer).
PHENOTYPE: Mice homozygous for a null allele exhibit osteopetrosis, decreased CD8+ T cells involved in tumor rejection, decreased uterine NK cells, and abnormal implantation site morphology. [provided by MGI curators]
  • synonyms:
  • DAP10,
  • KAP10,
  • hematopoietic cell signal transducer,
  • Hcst

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For