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Protein Coding Gene : Aen apoptosis enhancing nuclease
Primary Identifier  MGI:1915298 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  68048
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable DNA exonuclease activity. Predicted to be involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and response to ionizing radiation. Predicted to act upstream of or within DNA damage response and apoptotic process. Predicted to be located in nuclear membrane; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Is expressed in cerebral cortex and telencephalon. Orthologous to human AEN (apoptosis enhancing nuclease).
  • synonyms:
  • RIKEN cDNA 2700083B06 gene,
  • Isg20l1,
  • Aen,
  • 2700083B06Rik,
  • apoptosis enhancing nuclease,
  • interferon stimulated exonuclease gene 20-like 1
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Features --> Cross References

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0 Canonical

0 CDSs

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3 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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Genes --> Homologs

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Gene --> Expression annotations

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Disease

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