Primary Identifier | MGI:109326 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 12176 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables identical protein binding activity. Involved in several processes, including negative regulation of reactive oxygen species metabolic process; regulation of aerobic respiration; and regulation of mitochondrion organization. Acts upstream of or within brown fat cell differentiation; intrinsic apoptotic signaling pathway; and response to bacterium. Located in mitochondrial membrane and postsynaptic density. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; musculoskeletal system; and nasal epithelium. Orthologous to human BNIP3 (BCL2 interacting protein 3). PHENOTYPE: Mice homozygous for a null allele exhibit decreased post-ischemic ventricular remodeling. [provided by MGI curators] |