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Protein Coding Gene : Bnip3 BCL2/adenovirus E1B interacting protein 3

Primary Identifier  MGI:109326 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  12176
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables identical protein binding activity. Involved in several processes, including negative regulation of reactive oxygen species metabolic process; regulation of aerobic respiration; and regulation of mitochondrion organization. Acts upstream of or within brown fat cell differentiation; intrinsic apoptotic signaling pathway; and response to bacterium. Located in mitochondrial membrane and postsynaptic density. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; musculoskeletal system; and nasal epithelium. Orthologous to human BNIP3 (BCL2 interacting protein 3).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased post-ischemic ventricular remodeling. [provided by MGI curators]
  • synonyms:
  • Bnip3,
  • BCL2/adenovirus E1B interacting protein 3,
  • Nip3,
  • MGD-MRK-38371

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For