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Protein Coding Gene : Erlin2 ER lipid raft associated 2
Primary Identifier  MGI:2387215 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  244373
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable cholesterol binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in ERAD pathway; SREBP signaling pathway; and negative regulation of lipid biosynthetic process. Predicted to act upstream of or within cholesterol metabolic process. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum; and membrane raft. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 18. Orthologous to human ERLIN2 (ER lipid raft associated 2).
  • synonyms:
  • expressed sequence C87251,
  • Spfh2,
  • BC036333,
  • C87251,
  • MGC:27952,
  • ER lipid raft associated 2,
  • Erlin2,
  • cDNA sequence BC036333,
  • MGI:2142881,
  • SPFH domain family, member 2
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Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Interactions

2 Pathways

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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