| Primary Identifier | MGI:894694 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 108148 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable manganese ion binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation and protein maturation. Predicted to be located in Golgi stack and perinuclear region of cytoplasm. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; floor plate; lens; lung mesenchyme; and submandibular gland primordium. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human GALNT2 (polypeptide N-acetylgalactosaminyltransferase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased circulating HDL cholesterol levels under both chow- and Western diet-fed conditions, a marked elevation in fasting triglyceride levels, and delayed postprandial triglyceride clearance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
