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Protein Coding Gene : Pdgfd platelet-derived growth factor, D polypeptide

Primary Identifier  MGI:1919035 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  71785
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable platelet-derived growth factor receptor binding activity. Acts upstream of or within cellular response to amino acid stimulus and regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in bladder; brain; and urethra of male. Human ortholog(s) of this gene implicated in prostatic hypertrophy. Orthologous to human PDGFD (platelet derived growth factor D).
PHENOTYPE: Mice homozygous for a knock-out allele show a mild vascular phenotype characterized by abnormal pericyte morphology within cardiac tissue, slightly increased systolic and diastolic blood pressure, and altered serum levels of calcium and chloride ions. [provided by MGI curators]
  • synonyms:
  • 1110003I09Rik,
  • Pdgfd,
  • RIKEN cDNA 1110003I09 gene,
  • platelet-derived growth factor, D polypeptide

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For