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Protein Coding Gene : Fut4 fucosyltransferase 4

Primary Identifier  MGI:95594 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  14345
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables alpha-(1->3)-fucosyltransferase activity. Involved in lymphocyte migration into lymph node; positive regulation of leukocyte tethering or rolling; and positive regulation of neutrophil migration. Located in cell periphery and cell surface. Is expressed in several structures, including ear; embryo ectoderm; extraembryonic component; genitourinary system; and spinal cord. Orthologous to human FUT4 (fucosyltransferase 4).
PHENOTYPE: Mice homozygous for a knock-out allele show a modest increase in blood neutrophils, monocytes and eosinophils, and increased leukocyte rolling velocities. [provided by MGI curators]
  • synonyms:
  • Ssea1,
  • LeX,
  • Fut4,
  • MGD-MRK-9894,
  • FucT-IV,
  • 3-fucosyl-N-acetyl-lactosamine epitope,
  • fucosyltransferase 4,
  • SSEA-1,
  • expressed sequence AI451562,
  • FAL,
  • AI451562,
  • MGI:2143062

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For