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Protein Coding Gene : Angptl6 angiopoietin-like 6

Primary Identifier  MGI:1917976 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  70726
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable signaling receptor binding activity. Predicted to act upstream of or within angiogenesis and cell differentiation. Located in secretory granule. Is expressed in brain. Used to study obesity. Orthologous to human ANGPTL6 (angiopoietin like 6).
PHENOTYPE: Most mice homozygous for a knock-out allele die around E13 with cardiovascular defects; survivors develop obesity, lipid accumulation in skeletal muscle and liver, hyperglycemia and hyperinsulinemia, and insulin resistance accompanied by reduced energy expenditure and whole-body oxygen consumption. [provided by MGI curators]
  • synonyms:
  • AGF,
  • Angiopoietin-related growth factor,
  • angiopoietin-like 6,
  • Angptl6,
  • RIKEN cDNA 6330404E11 gene,
  • 6330404E11Rik,
  • Arp5

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1 Transgenic Expressors

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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