| Primary Identifier | MGI:2143057 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 208084 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including ATP binding activity; helicase activity; and magnesium ion binding activity. Predicted to be involved in DNA duplex unwinding; DNA replication; and negative regulation of telomere maintenance via telomerase. Predicted to act upstream of or within DNA recombination and DNA repair. Predicted to be located in chromosome, telomeric region. Predicted to be active in replication fork. Is expressed in several structures, including body cavity or lining; integumental system; thymus; ventricular layer; and vertebral axis musculature. Orthologous to human PIF1 (PIF1 5'-to-3' DNA helicase). PHENOTYPE: Mice homozygous for a knock-out allele are viable and overtly normal and show no evidence of increased sensitivity to DNA damage, genetic instability, reproducible telomere length alteration or other cellular abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
