| Primary Identifier | MGI:1277988 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 22294 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable beta-tubulin binding activity; chromatin binding activity; and transcription corepressor activity. Predicted to be involved in centrosome cycle and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within apoptotic process. Predicted to be located in centrosome; cytoplasm; and nucleus. Predicted to be part of RPAP3/R2TP/prefoldin-like complex. Is expressed in several structures, including cerebellum; neural retina; and telencephalon. Orthologous to human UXT (ubiquitously expressed prefoldin like chaperone). PHENOTYPE: Mice hemizygous or heterozygous for a germline null mutation display prenatal lethality. Male mice with testes-specific conditional loss of expression display azoospermia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
