| Primary Identifier | MGI:109524 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 22067 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables inositol 1,4,5 trisphosphate binding activity. Involved in neuron apoptotic process and phosphatidylserine exposure on apoptotic cell surface. Is active in presynapse. Is expressed in several structures, including alimentary system; endocrine gland; genitourinary system; immune system; and liver and biliary system. Orthologous to human TRPC5 (transient receptor potential cation channel subfamily C member 5). PHENOTYPE: Mice with homozygous null alleles of the gene exhibit diminished innate fear response with reduction in synaptic activation and strength in neurons of the amygdala. Mice homozygous for a null allele exhibit reduced female fertility with reduced prolactin levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
