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Protein Coding Gene : Rtl4 retrotransposon Gag like 4

Primary Identifier  MGI:3588192 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  619287
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Acts upstream of or within cognition and norepinephrine metabolic process. Is expressed in several structures, including brain; gonad; immune system; liver; and lung. Orthologous to human RTL4 (retrotransposon Gag like 4).
PHENOTYPE: Homozygous null mice exhibit abnormal behavior including hyperactivity and abnormal responses to a new environment, and abnormal working memory and cognition. Neuronal norepinephrine levesl are slow to recover after induced neurotransmitter release. Mortality, growth, kidney function, and reproductive system biology are all unaffected. [provided by MGI curators]
  • synonyms:
  • Zcchc16,
  • Mar4,
  • zinc finger, CCHC domain containing 16,
  • retrotransposon Gag like 4,
  • Rtl4,
  • C230031A03Rik,
  • RIKEN cDNA C230031A03 gene

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