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Protein Coding Gene : Shroom2 shroom family member 2
Primary Identifier  MGI:107194 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  110380
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables actin filament binding activity; beta-catenin binding activity; and protein domain specific binding activity. Involved in cell migration and melanosome organization. Acts upstream of or within cell-cell junction maintenance and negative regulation of actin filament depolymerization. Located in several cellular components, including adherens junction; apical plasma membrane; and bicellular tight junction. Colocalizes with cortical actin cytoskeleton. Is expressed in several structures, including blood vessel; central nervous system; epithelium; inner ear; and retina inner plexiform layer. Orthologous to human SHROOM2 (shroom family member 2).
  • synonyms:
  • Shrm2,
  • apical protein, Xenopus laevis-like,
  • MGI:2443591,
  • Apxl,
  • shroom family member 2,
  • Shroom2,
  • C630003H05Rik,
  • RIKEN cDNA C630003H05 gene,
  • MGD-MRK-35655
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

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Disease

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