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Protein Coding Gene : mt-Nd4 mitochondrially encoded NADH dehydrogenase 4
Primary Identifier  MGI:102498 Organism  mouse, laboratory
Chromosome  MT NCBI Gene Number  17719
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable NADH dehydrogenase (ubiquinone) activity and ubiquinone binding activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Parkinson's disease; macular degeneration; and schizophrenia. Orthologous to human MT-ND4 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4).
  • synonyms:
  • MGI:2138421,
  • MGI:2138441,
  • MGD-MRK-19335,
  • expressed sequence AU019464,
  • mitochondrially encoded NADH dehydrogenase 4,
  • expressed sequence AL024073,
  • mt-Nd4,
  • AU018658,
  • URF4,
  • expressed sequence AL024289,
  • AU019464,
  • MGI:2138399,
  • AL024073,
  • expressed sequence AU018658,
  • MGI:2138392,
  • AL024289
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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

5 Pathways

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Expression

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Phenotype

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Disease

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