First Author | Luciani MF | Year | 1994 |
Journal | Genomics | Volume | 21 |
Issue | 1 | Pages | 150-9 |
PubMed ID | 8088782 | Mgi Jnum | J:23029 |
Mgi Id | MGI:71825 | Doi | 10.1006/geno.1994.1237 |
Citation | Luciani MF, et al. (1994) Cloning of two novel ABC transporters mapping on human chromosome 9. Genomics 21(1):150-9 |
abstractText | The family of ATP binding cassette (ABC) transporters or traffic ATPases is composed of several membrane-associated proteins that transport a great variety of solutes across cellular membranes. Two novel mammalian members of the family, ABC1 and ABC2, have been identified by a PCR-based approach. They belong to a group of traffic ATPases encoded as a single multifunctional protein, such as CFTR, STE 6, and P-glycoproteins. Their peculiar structural features and close relationship to ABC transporters involved in nodulation suggest that ABC1 and ABC2 define a novel subgroup of mammalian traffic ATPases. |