First Author | Takahashi S | Year | 1995 |
Journal | FEBS Lett | Volume | 368 |
Issue | 3 | Pages | 455-60 |
PubMed ID | 7635198 | Mgi Jnum | J:30470 |
Mgi Id | MGI:77980 | Doi | 10.1016/0014-5793(95)00713-j |
Citation | Takahashi S, et al. (1995) Identification of two highly homologous presynaptic proteins distinctly localized at the dendritic and somatic synapses. FEBS Lett 368(3):455-60 |
abstractText | Through screening of a murine brain cDNA library, we have isolated two brain specific cDNAs encoding highly homologous proteins, named 921-L and 921-S, comprised of 134 amino acids with 80% identity. Immunohistological study with the mAbs raised against the bacterially expressed 921 proteins showed that 921-L protein is distributed at the dendritic region and 921-S at the neuronal somatic surface. Immuno-electron microscopic study revealed that both 921 proteins are localized at the presynaptic terminal, indicating that the 921 proteins are differentially expressed at the dendritic and somatic presynapses. |