First Author | Cachon-Gonzalez MB | Year | 1994 |
Journal | Proc Natl Acad Sci U S A | Volume | 91 |
Issue | 16 | Pages | 7717-21 |
PubMed ID | 8052649 | Mgi Jnum | J:19624 |
Mgi Id | MGI:67773 | Doi | 10.1073/pnas.91.16.7717 |
Citation | Cachon-Gonzalez MB, et al. (1994) Structure and expression of the hairless gene of mice. Proc Natl Acad Sci U S A 91(16):7717-21 |
abstractText | The hairless mutation of mice was caused by insertion of a murine leukemia virus. Starting with sequences flanking the provirus, a series of overlapping clones surrounding the viral integration site were obtained. By using a combination of sequencing, PCR, and exon-trapping techniques, the hairless gene was identified. It encodes a predicted protein of 1182 amino acids, including a potential zinc-finger domain. The expression patterns of the gene closely reflect the phenotype of animals carrying the hairless mutation. |