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Publication : Structure and expression of the hairless gene of mice.

First Author  Cachon-Gonzalez MB Year  1994
Journal  Proc Natl Acad Sci U S A Volume  91
Issue  16 Pages  7717-21
PubMed ID  8052649 Mgi Jnum  J:19624
Mgi Id  MGI:67773 Doi  10.1073/pnas.91.16.7717
Citation  Cachon-Gonzalez MB, et al. (1994) Structure and expression of the hairless gene of mice. Proc Natl Acad Sci U S A 91(16):7717-21
abstractText  The hairless mutation of mice was caused by insertion of a murine leukemia virus. Starting with sequences flanking the provirus, a series of overlapping clones surrounding the viral integration site were obtained. By using a combination of sequencing, PCR, and exon-trapping techniques, the hairless gene was identified. It encodes a predicted protein of 1182 amino acids, including a potential zinc-finger domain. The expression patterns of the gene closely reflect the phenotype of animals carrying the hairless mutation.
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