| First Author | Madaule P | Year | 1995 |
| Journal | FEBS Lett | Volume | 377 |
| Issue | 2 | Pages | 243-8 |
| PubMed ID | 8543060 | Mgi Jnum | J:30350 |
| Mgi Id | MGI:77862 | Doi | 10.1016/0014-5793(95)01351-2 |
| Citation | Madaule P, et al. (1995) A novel partner for the GTP-bound forms of rho and rac. FEBS Lett 377(2):243-8 |
| abstractText | Using the yeast two hybrid system and overlay assays we identified a putative rholrac effector, citron, which interacts with the GTP-bound forms of rho and rac1, but not with cdc42. Extensive homologies to known proteins were not observed. This 183 kDa protein contains a C6H2 zinc finger, a PH domain, and a long coiled-coil forming region including 4 leucine zippers and the rholrac binding site. We recently identified three others putative rho effectors characterized by a common rho binding motif. Citron does not share this motif and displays a distinctive protein organization, thus defining a separate class of rho partners. |
