First Author | Nakajima N | Year | 1993 |
Journal | Biochim Biophys Acta | Volume | 1171 |
Issue | 3 | Pages | 311-4 |
PubMed ID | 7916626 | Mgi Jnum | J:3919 |
Mgi Id | MGI:52424 | Doi | 10.1016/0167-4781(93)90072-l |
Citation | Nakajima N, et al. (1993) Nucleotide sequence of a mouse lamin A cDNA and its deduced amino acid sequence. Biochim Biophys Acta 1171(3):311-4 |
abstractText | We have cloned and determined the nucleotide sequence of a mouse lamin A cDNA. The clone contained the C-terminal two-thirds of the lamin A coding sequence and a 3' untranslated sequence with a poly(A) stretch. As has been reported for human lamin A/C cDNAs, a large part of the 5' sequence of our mouse lamin A clone was essentially identical with a previously reported mouse lamin C cDNA sequence, and the deduced C-terminal amino acid sequence shared strong homology with the human lamin A sequence. A putative deduced amino acid sequence for mouse lamin A, which was derived from our sequence and the published lamin C sequence, was 665 amino acids long. The degree of overall homology to the human sequence was more than 95%, and relatively more variation was scattered in the C-terminal lamin A-specific region. |