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Publication : Expression of the murine homeo box gene Hox 1.5 during embryogenesis.

First Author  Fainsod A Year  1987
Journal  Dev Biol Volume  124
Issue  1 Pages  125-33
PubMed ID  2444477 Mgi Jnum  J:8874
Mgi Id  MGI:57339 Doi  10.1016/0012-1606(87)90465-9
Citation  Fainsod A, et al. (1987) Expression of the murine homeo box gene Hox 1.5 during embryogenesis. Dev Biol 124(1):125-33
abstractText  The spatial pattern of expression of the murine homeo box-containing gene Hox 1.5 was studied during embryogenesis. In situ hybridization of single-stranded RNA probes to mouse embryo sections revealed a specific spatial distribution of the Hox 1.5 transcripts in mouse embryos 8.5 to 12.5 days postcoitum (p.c.). Analysis of mouse embryos 8.5 days p.c. showed that the gene is expressed in a spatially restricted manner. Expression appears to be limited to the central nervous system with an anterior boundary in the hindbrain and extending posteriorly through caudal regions of the spinal cord. The same spatial pattern of expression was observed in embryos 9.5 to 12.5 days p.c. These results show that the murine Hox 1.5 gene is expressed in a spatially restricted manner during embryonic development similar to the patterns observed in Drosophila homeotic genes.
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