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Publication : Molecular cloning of the zeta chain of the T cell antigen receptor.

First Author  Weissman AM Year  1988
Journal  Science Volume  239
Issue  4843 Pages  1018-21
PubMed ID  3278377 Mgi Jnum  J:9058
Mgi Id  MGI:57522 Doi  10.1126/science.3278377
Citation  Weissman AM, et al. (1988) Molecular cloning of the zeta chain of the T cell antigen receptor. Science 239(4843):1018-21
abstractText  The T cell antigen receptor is a multi-subunit receptor complex present on the surface of all mature and many developing T cells. It consists of clonotypic heterodimers noncovalently linked to five invariant chains that are encoded by four genes and referred to as the CD3 complex. The CD3 gamma, delta, and epsilon chains have been molecularly characterized. In this report the molecular cloning of a complementary DNA encoding the zeta chain of the murine T cell antigen receptor is described. The predicted protein sequence of the zeta chain suggests a structure distinct from those of any of the previously described receptor subunits.
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