First Author | Schenker T | Year | 2000 |
Journal | Biochim Biophys Acta | Volume | 1493 |
Issue | 1-2 | Pages | 255-8 |
PubMed ID | 10978534 | Mgi Jnum | J:75634 |
Mgi Id | MGI:2177159 | Doi | 10.1016/s0167-4781(00)00167-6 |
Citation | Schenker T, et al. (2000) BSPRY, a novel protein of the Ro-Ret family. Biochim Biophys Acta 1493(1-2):255-8 |
abstractText | Utilizing the yeast two-hybrid system we have identified a novel protein of the Ro-Ret family that was termed BSPRY. This protein is composed of a B-box, an alpha-helical coiled coil and a SPRY domain. BSPRY from human beings shares 80% sequence identity with the homologous protein from mice. The gene for BSPRY resides on human chromosome 9 and is specifically expressed in testis. It comprises six exons and five introns and possesses a GC rich promoter forming a typical CpG island. The function of BSPRY is not known, but several related proteins of the RBCC family have been implicated in cell transformation. |