| First Author | Auffray C | Year | 1981 |
| Journal | Gene | Volume | 13 |
| Issue | 4 | Pages | 365-74 |
| PubMed ID | 6790349 | Mgi Jnum | J:6561 |
| Mgi Id | MGI:55036 | Doi | 10.1016/0378-1119(81)90016-0 |
| Citation | Auffray C, et al. (1981) Mouse immunoglobulin A: nucleotide sequence of the structural gene for the alpha heavy chain derived from cloned cDNAs. Gene 13(4):365-74 |
| abstractText | The cDNAs complementary to mouse immunoglobulin alpha heavy chain mRNAs have been cloned into the PstI site of the plasmid vector pBR322. Recombinant plasmids have been identified by hybrid-arrested translation and purification of alpha heavy chain mRNA on DNA-DBM filters. The nucleotide sequence of the inserts encodes the constant and 3' untranslated regions of the alpha heavy chain mRNA. The CH3 domains of human and mouse alpha chains are highly homologous, including a 36 amino acid fragment not reported in the protein sequence (Robinson and Appella, 1980). As in the case of the mu secreted heavy chain, the alpha heavy chain contains a carboxy terminal piece of 20 amino acids. |
