| First Author | Harding PA | Year | 1996 |
| Journal | Gene | Volume | 169 |
| Issue | 2 | Pages | 291-2 |
| PubMed ID | 8647467 | Mgi Jnum | J:32107 |
| Mgi Id | MGI:79612 | Doi | 10.1016/0378-1119(95)00861-6 |
| Citation | Harding PA, et al. (1996) Characterization of the gene encoding murine heparin-binding epidermal growth factor-like growth factor. Gene 169(2):291-2 |
| abstractText | The mouse gene (mHB-EGF) encoding heparin-binding epidermal growth factor-like growth factor was isolated from a mouse 129SVJ genomic library. DNA sequence analysis confirmed that the clone contained six exons (I-VI) and five introns (A-E), and spanned approx. 14 kb of DNA. PCR analysis showed that introns A-E of mHB-EGF are 203 bp, 2.5 kb, 5.5 kb, 825 bp and 272 bp in length, respectively. These results establish that mHB-EGF is similar in organization to human HB-EGF (hHB-EGF). However, DNA sequence analysis of introns A-E of mHB-EGF failed to show significant overall homology with those of hHB-EGF. |
